The author highlights the problem of accounting changes in the spatial coordinates of geodetic stations in the global terrestrial reference frame. A brief description of the data center of high-precision GNSS-observations SOPAC and satellite geodetic network of the International GPS-service is given. The results of studies that experimentally determined the velocity of the Eurasian lithospheric plate (EU) are shown. The formulae describing the change in the azimuth of the trajectory and velocity of a point on the Earth's surface within the EU on the territory of the Russian Federation were obtained.